Oh my god, this is like my dream 2GR build, it's perfect. It's great the IS-F's titanium valves fit, that's very useful. That would, I think, make the 2GR the only 6 cylinder out there that has a non-custom titanium valve option.
If you can find a set of Inconel exhaust valves, you would theoretically be able to thin them a bit for lightness because at 800C, Inconel is much stronger than titanium or stainless steel. The IS-F exhaust valves seem to be Inconel since they were advertised as being high nickel and heat resistant, although I have no idea if they took advantage of that and made them lighter.
One more thing that may or may not be an issue is the titanium retainers. Supertech and Ferrea claim to DLC coat their retainers, but I have no idea where MWR's retainers come from. DLC coating is as far as I can tell essential on a street engine for preventing the springs from wearing away the retainers over time.
As far as the oil system goes, it looks pretty well baffled from the factory. As an upgrade, maybe look into the Ishihara Johnson crank scraper? (haven't read any actual user reviews) Gouky/Marc seems to think the stock engine is pretty well sorted out in that regard.